A desperate Charles Manson escapes with his Family to a desert hideout. There, prison camp-like conditions force two of the girls to make a life-or-death escape attempt. Meanwhile, Los Angeles is paralyzed with fear as the police fumble the investigation. But then Manson unexpectedly helps brings his reign of terror to an end. When a jailhouse confession comes to light, Helter Skelter reveals how the pieces of the puzzle finally come together for the law.
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